Symbol
Name
ID

Bag3
BCL2-associated athanogene 3
MGI:1352493

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Dilated cardiomyopathy	Hypertrophic cardiomyopathy	Restrictive cardiomyopathy	Increased left ventricular end-diastolic volume	Mitral regurgitation	Congestive heart failure
Disease(s) Associated with BAG3	Dilated cardiomyopathy	Hypertrophic cardiomyopathy	Restrictive cardiomyopathy	Increased left ventricular end-diastolic volume	Mitral regurgitation	Congestive heart failure
dilated cardiomyopathy 1HH
myofibrillar myopathy 6

Mouse Phenotypes

myocardial fiber degeneration

increased heart weight

enlarged heart

cardiac fibrosis

dilated cardiomyopathy

decreased cardiac muscle contractility

abnormal fetal cardiomyocyte physiology

abnormal heart echocardiography feature

abnormal myocardial fiber physiology

increased cardiomyocyte apoptosis

congestive heart failure

Availability

Mouse Genotype

Bag3^{Gt(OST16086)Lex}/Bag3^{Gt(OST16086)Lex}

Bag3^{tm1c(EUCOMM)Hmgu}/Bag3^{tm1c(EUCOMM)Hmgu}
Tg(Myhca-cre)1Abel/0 (conditional)

Bag3^{tm1c(EUCOMM)Hmgu}/Bag3^tm1.1Chen
Tg(Myhca-cre)1Abel/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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